Anti Vascular Endothelial Growth Factor Monoclonal Antibody

The Anti-VEGFA Mouse Monoclonal Antibody is a high-specificity reagent designed for the detection of Vascular Endothelial Growth Factor A (VEGFA), a key regulator of angiogenesis and vascular development. This antibody is validated for Western Blot, ELISA, and Immunohistochemistry on paraffin-embedded tissues, making it an essential tool for cancer research, cardiovascular studies, and developmental biology.

Background
VEGFA is a heparin-binding growth factor that plays a central role in physiological and pathological angiogenesis. It promotes endothelial cell proliferation, migration, and vascular permeability. VEGFA is upregulated in many tumors and is associated with tumor progression, metastasis, and poor prognosis. It is also implicated in diabetic microvascular complications, atherosclerosis, and POEMS syndrome.

Research Applications
Ideal for:

• Angiogenesis and vascular biology studies

• Cancer research and tumor microenvironment analysis

• Cardiovascular and metabolic disease models

• Developmental biology and signal transduction pathways

• ELISA-based quantification of VEGF in biological samples

Cellular Localization
Secreted; isoforms vary in heparin-binding and extracellular matrix association (VEGF121, VEGF165, VEGF189).

Note: For research use only. Not for diagnostic or therapeutic use.