Anti-DARPP-32

Overview
The Anti-DARPP-32 Rabbit Polyclonal Antibody is a highly specific, affinity-purified reagent designed for the detection of DARPP-32, a key dopamine and cAMP-regulated phosphoprotein essential for neuronal signaling. Validated for Western Blot and Immunohistochemistry, this antibody is a trusted tool for neuroscience, addiction research, and studies of dopaminergic neurotransmission.

Background
DARPP-32 is a critical modulator of dopaminergic signaling. When phosphorylated at Thr-34, it inhibits protein phosphatase 1; when phosphorylated at Thr-75, it inhibits PKA. Its activity is implicated in responses to addictive substances, making it a focal point in neuropsychiatric and addiction research.

Research Applications

• Dopamine signaling and neurotransmitter studies

• Addiction and substance abuse research

• Neurological and psychiatric disorder models

• Striatal and neuronal pathway analysis

Our Guarantee
We stand behind our antibodies. If this product does not perform as described, we offer a free replacement or full refund.

Note: For research use only. Not for diagnostic or therapeutic use.